17 Similarly, a significant increase in hydration was observed at months 1 and 3 after treatment, as measured by Corneometer, and a trend toward significance was observed with the MoistureMeter at more superficial depths (XS probe) and no difference observed with the MoistureMeter at deeper depths (S probe), indicating a decreasing impact on hydration with increasing depth.
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A Prospective, Open-Label Study to Evaluate the Impact of VYC-12L Injection on Skin Quality Attributes in Healthy Volunteers.
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Interestingly, ultrasound measurements showed a trend for an increase in density while the skin thickness was maintained.