Barely Significant
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A Prospective, Open-Label Study to Evaluate the Impact of VYC-12L Injection on Skin Quality Attributes in Healthy Volunteers.

Clin Cosmet Investig Dermatol · 2022 · PMC8921677 · PMID 35300433

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a trend toward significanceno p-value reported
17 Similarly, a significant increase in hydration was observed at months 1 and 3 after treatment, as measured by Corneometer, and a trend toward significance was observed with the MoistureMeter at more superficial depths (XS probe) and no difference observed with the MoistureMeter at deeper depths (S probe), indicating a decreasing impact on hydration with increasing depth.

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showed a trendno p-value reported
Interestingly, ultrasound measurements showed a trend for an increase in density while the skin thickness was maintained.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.