ZEB1 transcription factor promotes immune escape in melanoma.

J Immunother Cancer · 2022 · PMC8921918 · PMID 35288462

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Finally, we evaluated the activation state of CD8 + T cells by performing Granzyme B, Ki-67 and PD-1 staining, which showed a trend toward decreased expression in ZEB1 high tumors, suggesting a lower level of activation ( online supplemental figure 6C ).

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