Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters.

Med · 2022 · PMC8926874 · PMID 35313451

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Despite significantly reduced overall pathology, however, Omicron-infected hamsters had similar numbers of SARS nucleocapsid (SARS-N)-positive cells in lung as compared with WA1/2020-infected hamsters ( Figure 3 Q) but showed a trend toward fewer Iba-1-positive cells (macrophages) and myeloperoxidase-positive cells (neutrophils) per unit area of lung ( Figures 3 R, 3S, and S1 ).

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