Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.

Sci Rep · 2022 · PMC8927592 · PMID 35296692

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nominally significantno p-value reported

Six SNPs had nominally significant associations to more than one endpoint. rs11082257, an intronic SNP in PIK3C3 on chromosome 18q12.3, was associated with decreased risk for any IA (HR = 0.88, 95% CI 0.78–0.99, P = 0.031), mIAA-first (HR = 0.76, 95% CI 0.62–0.93, P = 0.008) and T1D (HR = 0.79, 95% CI 0.65–0.97, P = 0.022). rs301707

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