The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model.

Compared to the case with an uninfected control or a vehicle control (DMSO), the addition of PsA during the infection reduced the amount of ExoU PLA 2 activity detected in enriched mito-MAM fractions, although the data did not reach statistical significance ( Fig. 3E and F ).

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