CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth.

Cell Mol Life Sci · 2022 · PMC8930798 · PMID 35298717

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DRG also expressed mRNA for IGF-1, and this endogenous expression showed a trend of reduction in the diabetic state which was significantly up-regulated by exogenous hIGF-1 treatment (Fig. 2 A).

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