Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function.

J Exp Med · 2022 · PMC8932531 · PMID 35103755

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showed a trendno p-value reported

In obese mice, CD8 T cells significantly increased kynurenine uptake, proliferated more, and showed a trend toward increased GzmB expression, but no significant differences in IFN-γ, CD98, or pS6 were detected at this time point ( Fig. 6, A and B ).

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