Even though some effects reported in this study did not reach statistical significance (mostly due to high variations between individual animals within a group, as frequently observed in studies involving pigs), the overall tendency of the results strongly suggests adverse effects of DON on PRRSV vaccine efficacy and disease.
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The mycotoxin deoxynivalenol (DON) can deteriorate vaccination efficacy against porcine reproductive and respiratory syndrome virus (PRRSV) at subtoxic levels.
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