Despite the large effect, the analysis failed to reach statistical significance, which can be attributed to the small number of included trials ( n = 4), their considerable effect heterogeneity ( I 2 = 92.4%), and the small sample sizes, considering that three out of four studies have a total of 40 participants (i.e., maximum of 20 per group).
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Comment on: "Attempting to Separate Placebo Effects from Exercise in Chronic Pain: A Systematic Review and Meta-analysis".
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