Levels of the microglial activation marker TREM2 were higher in both cortex and hippocampus of App NL-G-F -Veh mice compared to the WT control (WT-Veh) group, whereas effects upon treatment with LMs did not reach statistical significance (Fig. 4b, c ).
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Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in App<sup>NL-G-F/NL-G-F</sup> mice.
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