High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis.

Front Immunol · 2022 · PMC8940299 · PMID 35330910

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hedged sentence

0.6350

closest p · 12.7× alpha

0.6350

boldest claim

The sentences

did not reach statistical significancep = 0.635not close (p > 0.1)

We sought for the discriminative potential of KFLC-index to detect both double-positive (OCGBs and OCMBs) patients, and we observed that pwMS with unique OCGB pattern had a lower median KFLC-index (54.9 (38.4–122.8)) as compared to those with OCGBs and OCMBs (90.6 (30.7–143.3)), but this difference did not reach statistical significance ( p = 0.635) ( Figure 1B ).

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