The combination of all 4 biomarkers into a composite panel increased the AUC to 0.75 in the training cohort and to 0.90 in the validation cohort (supplemental Figure 4), although these improvements in AUC did not reach statistical significance.
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A biomarker panel for risk of early respiratory failure following hematopoietic cell transplantation.
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WFDC2 and IL-6 had increased hazard ratios (HRs), but did not quite reach statistical significance (supplemental Figure 2; supplemental Table 7).