Lack of influence of dexmedetomidine on rat glomus cell response to hypoxia, and on mouse acute hypoxic ventilatory response.

While there was indeed an increase in mean magnitude of HVD with increasing dose of dexmedetomidine [ Table 1 ], this did not reach statistical significance ( P = 0.127), and the effect on the mean value may be due to one animal with an especially pronounced reduction in AHVR in the 500 μg.kg -1 group [see Figure 2 ].

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