Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice.

However, we observed a clear trend towards a diminished number of immune cells in tumors from Stat3 Δ Col1a2 mice as compared to the controls ( Stat3 fl/fl ) for markers F4/80 and CD3 but not for MPO ( Figure 5 C).

also in 19,460 other papers

In fact, mice with a constitutively active STAT3 protein revealed a highly significant change with clearly enhanced tumorigenesis as compared to controls ( Figure 2 D), although there was no evidence for invasive tumor growth or metastasis.

also in 132,142 other papers