Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2.

Hum Mol Genet · 2022 · PMC8947322 · PMID 34590679

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did not reach statistical significanceno p-value reported

( 45 ) observed a decrease in plasma PCSK9 concentration in Tm6sf2 −/− mice compared to wild-type mice, but this reduction did not reach statistical significance.

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