Multi-Omics Characterization of Early- and Adult-Onset Major Depressive Disorder.

However, a signal of three SNVs in tight linkage-disequilibrium (LD) in an intron of the Sterile Alpha Motif Domain Containing 3 ( SAMD3) gene (chromosome 6) achieved near statistical significance in the CO-MED cohort, with the tag SNV (rs870816) reaching p = 8.8 × 10 −8 ( t = −4.49).

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