Barely Significant
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Efficacy and safety of botulinum toxin type A in distraction osteogenesis of the lower extremities: a meta-analysis of randomized controlled trials.

BMC Musculoskelet Disord · 2022 · PMC8953065 · PMID 35337325

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showed a trendno p-value reported
Results showed a trend of pain reduction at mid-distraction, less parenteral pain medication use, improved quality of life, higher functional mobility scores, and fewer major adverse events in patients who received BoNT compared with controls, although these differences were not statistically significant.

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