Loss of Microglial Insulin Receptor Leads to Sex-Dependent Metabolic Disorders in Obese Mice.

However, we observed a strong trend for increased BW and BW gain from week 3 onwards in obese InsR-KO females, compared to InsR-Ctrl ( Figure 1 H,I).

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We observed a lower locomotor activity in HFD-fed, InsR-Ctrl male mice compared to InsR-KO mice during the light (inactive) phase ( Figure 2 K,L), which was borderline significant for 24 h ( Figure 2 M).

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