Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT<sub>1A</sub> Receptor Biased Agonist.

Pharmaceuticals (Basel) · 2022 · PMC8954942 · PMID 35337135

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did not reach statistical significancep > 0.05actually significant

NLX-101 tended to increase the expression of pERK(1/2) at 30 min after its administration although this difference did not reach statistical significance (+94%, t = 1.634, df = 8, p > 0.05, two-tailed Student’s t -test).

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