Assessment of the Effects of the Synbiotic Combination of <i>Bifidobacterium longum</i> subsp. <i>infantis</i> CECT 7210 and Oligofructose-Enriched Inulin Against Digestive Bacterial Infections in a Piglet Model.

Front Microbiol · 2022 · PMC8957890 · PMID 35350617

Europe PMC DOI

hedged sentences

0.0780

closest p · 1.6× alpha

0.1520

boldest claim

The sentences

an increasing trendp = 0.078so close (0.05 < p ≤ 0.1)

Crypt depth showed an increasing trend due to the synbiotic administration on day 4 PI in the Salmonella trial ( p = 0.078), but, contrarily, a decreasing one on day 3 in the ETEC F4 trial ( p = 0.081).

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did not reach statistical significancep = 0.132not close (p > 0.1)

Regarding TNF-α, animals challenged with ETEC F4 presented higher concentrations than non-challenged pigs on day 7 PI (58.9, 57.2, 48.1 and 43.1 pg./ml for IC, IS, NIC and NIS, respectively; p = 0.010) and a similar pattern was found after the Salmonella challenge, although in this case, the differences did not reach statistical significance (125, 135, 124 and 101 pg./ml for IC, IS, NIC and NIS, respectively, day 8 PI; p = 0.132).

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a numerical trendp = 0.152not close (p > 0.1)

The effects of the ETEC F4 challenge were milder, with only a numerical trend seen for a lower ADFI in the post-inoculation period (333.65 vs. 367.95 g for challenged and non-challenged groups, respectively, p = 0.152).

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