Barely Significant
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Cigarette Smoking and Human Gut Microbiota in Healthy Adults: A Systematic Review.

Biomedicines · 2022 · PMC8962244 · PMID 35203720

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showed a trendno p-value reported
found that tobacco use showed a trend toward association with the microbiota using UniFrac distance [ 38 ]. 3.3.

also in 53,322 other papers

a decreasing trendno p-value reported
However, a decreasing trend of the Shannon index, both among tobacco [ 28 , 44 ] and among e-cigarettes smokers [ 41 ], was found in studies that did not produce statistically significant results.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.