An Integrative Approach to Characterize the Early Phases of Dimethylhydrazine-Induced Colorectal Carcinogenesis in the Rat.

Biomedicines · 2022 · PMC8962270 · PMID 35203618

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0710

boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

Effect of DMH on the Activity of Colonic Antioxidant Enzymes Although the differences between control and CRC groups did not reach statistical significance ( p > 0.05), the treatment with DMH decreased the antioxidant levels of the enzymes SOD and CAT ( Table 7 ).

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marginally significantp = 0.071so close (0.05 < p ≤ 0.1)

The alpha-diversity (Shannon and Chao1 indexes) was evaluated for each group at each timepoint, and only the Chao1 index showed a marginally significant difference when CRC1 and CRC2 rats were compared ( p = 0.071) ( Figure 7 A).

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