Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice.

Aging Pathobiol Ther · 2020 · PMC8963792 · PMID 35356005

Europe PMC DOI

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closest p · 1.0× alpha

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did not reach statistical significancep> 0.05actually significant

Tg(TXN2) +/0 mice had slightly longer mean (8.2%), median (8.9%), and 10th percentile (8.1%) lifespans compared to WT mice, however, these differences did not reach statistical significance (p> 0.05).

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