Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike.

Elife · 2022 · PMC8963877 · PMID 35323111

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did not reach statistical significanceno p-value reported

In all cases, the mAbs stabilized the RBD-up conformation of SΔTM D614 as compared to the unbound spike, although none to the extent seen for ACE2 ( Figure 4A ); and the effect of REGN10987 and S309 did not reach statistical significance.

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