Gene signatures in patients with early breast cancer and relapse despite pathologic complete response.

NPJ Breast Cancer · 2022 · PMC8964729 · PMID 35351903

Europe PMC DOI

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0.0550

closest p · 1.1× alpha

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boldest claim

The sentences

showed a trendP = 0.055so close (0.05 < p ≤ 0.1)

Patients with distant relapse also showed a trend for decreased interferon gamma (IFNγ) signaling (logFC = −0.759; 95% confidence interval (CI): −1.534 to 0.172; P = 0.055) and significantly higher homologous recombination deficiency (HRD) signature expression in the primary tumor versus controls (Fig. 3c ; Supplementary Table S1 ).

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