Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody.

PLoS One · 2022 · PMC8967028 · PMID 35353868

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did not reach statistical significanceno p-value reported

There was a relatively high variability in the virus titre data obtained with the plaque assay for all groups, and hence the observed changes in live virus titres between groups treated with VHH-72-Fc variants did not reach statistical significance.

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