Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.

48–50 We also identified lead SNPs (or the next most significant candidate SNPs) that were nominally significant at P < 0.05 in each independent sample. 48 , 50 Functional annotation Candidate SNPs were functionally annotated to characterize their biological significance ( Supplementary material ), identify SNPs with pathogenic potential [Combined Annotation Dependent Depletion (CADD) scores >12.37] 51 and highlight putative causal genes.

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