Barely Significant
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Treatment with neurohormonal inhibitors and prognostic outcome in pulmonary arterial hypertension with risk factors for left heart disease.

World J Crit Care Med · 2022 · PMC8968482 · PMID 35433314

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a significant trendno p-value reported
In the same way, data from the COMPERA (Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Arterial Hypertension) and other registry reports showed a significant trend towards an increased age and a higher percentage of cardiovascular comorbidities at diagnosis of PAH, together with a weaker response to targeted PAH therapy[ 6 , 7 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.