Western blot results indicated that mitochondrial complexes (CI subunit NDUFB8, CII subunit SDH, CIII subunit UQCRC, and CV subunit ATP5A) showed a trend toward increased abundance after TMAVA treatment (Supplementary Fig. 7i, j ).
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Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy.
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