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Point Mutations in the <i>FLT3</i>-ITD Region Are Rare but Recurrent Alterations in Adult AML and Associated With Concomitant <i>KMT2A</i>-PTD.

Front Oncol · 2022 · PMC8977490 · PMID 35387132

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showed a trendno p-value reported
However, patients with dual FLT3 non-ITD and KMT2A -PTD mutations showed a trend for inferior outcome, which points at a functional interaction in this subset of AML.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.