approached significancep = 0.052
However, the average intensity of THSD1 among medium‐sized EVs approached significance ( p = 0.052), with low resilient individuals having the greater average intensity of THSD1 among medium‐sized EVs (MED: 10.54; IQR: 2.32, 20.95) compared to high resilient individuals (MED: 3.29; IQR: 0.97, 5.24). 3.6 Feature selection based on EV feature changes in response to stress Provided that many definitions of resilience rest on how an individual responds to a stressor, we investigated whether changes in the EV profile in response to 48 h of sleep and caloric restriction would differ between those that are highly resilient compared to low resilient peers.