Meiotic, genomic and evolutionary properties of crossover distribution in Drosophila yakuba.

Analyses focusing on genes likely under positive selection for amino acid changes show either no significant or a weakly significant positive association between crossover rates and rates of protein evolution [ 98 , 101 – 105 ].

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These analyses reveal a highly significant tendency for crossovers in 2CO chromatids to be more distant than expected (positive interference) for all chromosome arms except 2R , with a weak, albeit significant, departure from genome-wide expectations ( P = 0.046) that becomes highly significant when removing 2R ( P < 1×10 −6 ).

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