Interestingly, in accordance with our results using imatinib (acute treatment), we found that NPA mice treated with the nilotinib supplemented diet showed a significant increase in neuronal survival at posterior lobules 7 and 8, whereas mice treated with a neurotinib supplemented diet showed a trend for an increase in neuron survival that was not significant.
← all excerpts
c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
1
—
—