LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs.

The pulmonary tumor nodule formation was significantly decreased in anti-gp49 mAb-treated tumor-bearing mice, similar to that in anti-PD-1-treated and combination-treated B16F10 tumor-bearing mice (Supplemental Figure 2B, left), and anti-gp49 mAb and/or anti-PD-1 mAb treatment also showed a trend toward reducing the liver metastasis in B16F10-bearing mice (Supplemental Figure 2B, right).

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