Barely Significant
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Enhancement of prime editing via xrRNA motif-joined pegRNA.

Nat Commun · 2022 · PMC8986804 · PMID 35387980

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did not reach statistical significancep = 0.15not close (p > 0.1)
Although some of the differences from these comparisons did not reach statistical significance ( p = 0.15, p = 0.13 and p < 0.05, respectively), such patterns of indel rates by xrPE in reference to the PE3 groups roughly correlate with the xrPE-associated 2.1-, 1.8-, and 2.5-fold of overall efficiency enhancements for the 3 types of modifications (see Figs. 3 c and 4b ).

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