highly significantp < 0.001
A two-way ANOVA of the histamine concentrations resulted in a statistically highly significant difference between mice with impaired and normal kidney function ( F (4, 44) = 23.2, p < 0.001) (Fig. 4 b).
A two-way ANOVA of the histamine concentrations resulted in a statistically highly significant difference between mice with impaired and normal kidney function ( F (4, 44) = 23.2, p < 0.001) (Fig. 4 b).
Data using inhibition of HNMT with metoprine showed a trend towards the involvement of endogenous DAO in histamine inactivation.