Modification of BRCA1-associated breast cancer risk by HMMR overexpression.

This association was identified from the results of the variant rs299290 (T > C; minor allele frequency = 0.25), which was not significant at the genome-wide level, but nominally significant in two study phases 12 , 14 , 19 (combined log-relative risk effect = 0.044, p = 0.001).

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