Optimized cyclosporine starting dose may reduce risk of acute GvHD after allogeneic hematopoietic cell transplantation: a single-center cohort study.

Bone Marrow Transplant · 2022 · PMC8993684 · PMID 35132203

Europe PMC DOI

hedged sentence

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

failed to reach statistical significancep = 0.082so close (0.05 < p ≤ 0.1)

Albeit the analysis of aGvHD grade III–IV failed to reach statistical significance ( p = 0.082) probably due to the limited statistical power of patients with aGvHD grade III–IV, the analysis also confirm that higher starting of 5 mg/kg/d could also reduce the incidence of aGvHD grade III–IV (Table 2 ).

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