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Baricitinib further enhances disease-modifying effects by uncoupling the link between disease activity and joint structural progression in patients with rheumatoid arthritis.

Ann Rheum Dis · 2022 · PMC8995831 · PMID 35193872

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While there was a trend towards better structural efficacy in patients with higher disease activity states also with baricitinib monotherapy compared with MTX monotherapy, this did not reach statistical significance.

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