Germline Variants in Angiogenesis-Related Genes Contribute to Clinical Outcome in Head and Neck Squamous Cell Carcinoma.

Cancers (Basel) · 2022 · PMC8997703 · PMID 35406617

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

only marginally significantp = 0.085so close (0.05 < p ≤ 0.1)

In the whole group, the MMP2 rs7201 C variant conferred an increased risk of locoregional recurrence ( p log-rank = 0.025, HR 1.55, p = 0.037; Figure 1 I), while the association of TIMP2 rs7501477 T allele with poor LRFS was only marginally significant ( p log-rank = 0.068, HR 1.40, 95% confidence interval (CI) 0.95–2.07, p = 0.085.

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