Molecular Lego of Human Cytochrome P450: The Key Role of Heme Domain Flexibility for the Activity of the Chimeric Proteins.

Int J Mol Sci · 2022 · PMC8998974 · PMID 35408976

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a clear trendno p-value reported

None of the ARO-BMR proteins exhibited a full shift to 450 nm and a clear trend is present among the three different chimeras indicating that ARO-BMR has the highest content of active protein followed by ARO-BMR-3GLY and ARO-BMR-5GLY (data not shown).

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