Likewise, flow cytometry analyses suggested a trend towards increased proportions of CD27 hi CD8 + T cells (cluster 3), γδ T cells (cluster 4), and CD16 hi neutrophils (cluster 20) in SF and increased proportion of CD27 lo CD8 + T cells (clusters 8–11) in PB samples.; however, the differences in immune cell subsets between PB and SF T cells did not reach statistical significance (Supplementary Fig. 1e, f ).
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Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy.
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