Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells.

Further analysis of RORγt expression in the CD24 pos CD73 neg population showed that KI-PRS mice have slightly lower frequency and number of RORγt+ cells, although the data did not reach statistical significance ( Figure 2E ).

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