Effect of 15-mg Edoxaban on Clinical Outcomes in 3 Age Strata in Older Patients With Atrial Fibrillation: A Prespecified Subanalysis of the ELDERCARE-AF Randomized Clinical Trial.

JAMA Cardiol · 2022 · PMC9008564 · PMID 35416910

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did not reach statistical significanceno p-value reported

e for Elder Care Atrial Fibrillation Patients (ELDERCARE–AF) of 984 patients, results showed that very low-dose edoxaban reduced the incidence of stroke or systemic embolism consistently across these 3 age strata, with a numerically higher risk of major or clinically relevant nonmajor bleeding that did not reach statistical significance.

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