Global analysis of cell behavior and protein dynamics reveals region-specific roles for Shroom3 and N-cadherin during neural tube closure.

Our analysis of posterior shroom3 crispant junctions revealed a barely significant (p = 0.015) change in their bulk behavior ( Figure 11B , right).

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In the posterior, however, the majority of shroom3 crispant cells still strongly constricted, though collectively they displayed a mildly significant defect in apical constriction ( Figure 5C, D , right).

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