Tolerability of duloxetine in elderly and in non-elderly adults: a protocol of a systematic review and individual participant data meta-analysis of randomized placebo-controlled trials.

Syst Rev · 2022 · PMC9013122 · PMID 35428340

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did not reach statistical significanceno p-value reported

(2018) found similar results, observing a significant association between the mean age of participants and response to duloxetine (odds ratio (OR) = 1.86, confidence interval (CI) 95% = 1.66–2.08) with an association between age and number of drop-outs under duloxetine (OR = 1.10, CI 95% = 0.97–1.24) [ 13 ], although the latter result did not reach statistical significance.

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