A genome-wide association study of >116,000 single nucleotide variants (SNPs) in 40 ME/CFS patients and 40 controls reported nominally significant association of ME/CFS with variants in 65 SNPs, including markers in the clock gene NPAS2 ( Smith et al., 2011 ).
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Circadian rhythm disruption in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Implications for the post-acute sequelae of COVID-19.
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