As shown in Figure 6 , treatment with 25 mg/kg of panduratin A for 8 weeks showed a significantly decrease in renal cystic index and showed a trend of reduced percentage of kidney weight to body weight compared to vehicle-treated rats.
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Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease.
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