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Oral cryotherapy for management of chemotherapy-induced oral mucositis in haematopoietic cell transplantation: a systematic review.

BMC Cancer · 2022 · PMC9027418 · PMID 35459129

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A new drug, palifermin reduces the incidence of mucositis after high dose methotrexate, however, the clinical benefit fell short of expectations and did not reach statistical significance in allogeneic HCT [ 50 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.