Influence of Receptor Polymorphisms on the Response to α-Adrenergic Receptor Blockers in Pheochromocytoma Patients.

Biomedicines · 2022 · PMC9028965 · PMID 35453646

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nominally significantno p-value reported

The haplotype analyses revealed nominally significant associations of haplotype A-C-A-C in block 6, consisting of SNPs rs10515807, rs6888306, rs13162302, and rs11750092 in the ADRA1B gene with both a higher dose of α-adrenergic receptor blockers (OR = 3.30; p = 0.044) and a higher number of side effects (OR = 3.51; p = 0.007) ( Table 4 ).

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